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Synthesis of Oxazocenones via Gold(I)-Catalyzed 8-Endo-Dig Hydroalkoxylation of Alkynamides

[Image: see text] Several benzoxazocenones have been found to exhibit novel cellular activities. In the present study, we report a gold(I)-catalyzed 8-endo-dig hydroalkoxylation reaction of alkynamides to access analogous oxazocenone scaffolds. This methodology provided an advanced intermediate, whi...

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Detalles Bibliográficos
Autores principales:	Scully, Stephen S., Zheng, Shao-Liang, Wagner, Bridget K., Schreiber, Stuart L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323038/ https://www.ncbi.nlm.nih.gov/pubmed/25569027 http://dx.doi.org/10.1021/ol503273v

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