AID to overcome the limitations of genomic information by introducing somatic DNA alterations

The immune system has adopted somatic DNA alterations to overcome the limitations of the genomic information. Activation induced cytidine deaminase (AID) is an essential enzyme to regulate class switch recombination (CSR), somatic hypermutation (SHM) and gene conversion (GC) of the immunoglobulin ge...

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Detalles Bibliográficos
Autores principales: Honjo, Tasuku, Muramatsu, Masamichi, Nagaoka, Hitoshi, Kinoshita, Kazuo, Shinkura, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323042/
https://www.ncbi.nlm.nih.gov/pubmed/25873751

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