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LKB1 tumor suppressor: Therapeutic opportunities knock when LKB1 is inactivated
LKB1 is commonly thought of as a tumor suppressor gene because its hereditary mutation is responsible for a cancer syndrome, and somatic inactivation of LKB1 is found in non-small cell lung cancer, melanoma, and cervical cancers. However, unlike other tumor suppressors whose main function is to eith...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chongqing Medical University
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323096/ https://www.ncbi.nlm.nih.gov/pubmed/25679014 http://dx.doi.org/10.1016/j.gendis.2014.06.002 |