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Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas
BACKGROUND: Although the involvement of intra-tumor genetic heterogeneity in tumor progression, treatment resistance, and metastasis is established, genetic heterogeneity is seldom examined in clinical trials or practice. Many studies of heterogeneity have had prespecified markers for tumor subpopul...
Autores principales: | Mroz, Edmund A., Tward, Aaron M., Hammon, Rebecca J., Ren, Yin, Rocco, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323109/ https://www.ncbi.nlm.nih.gov/pubmed/25668320 http://dx.doi.org/10.1371/journal.pmed.1001786 |
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