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Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice
BACKGROUND: Neuroinflammation often results in enduring cognitive impairment and is a risk factor for postoperative cognitive dysfunction. There are currently no effective treatments for infection-induced cognitive impairment. Previous studies have shown that the iron chelator deferoxamine (DFO) can...
Autores principales: | Zhang, Xiao-Ying, Cao, Jiang-Bei, Zhang, Li-Ming, Li, Yun-Feng, Mi, Wei-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323121/ https://www.ncbi.nlm.nih.gov/pubmed/25644393 http://dx.doi.org/10.1186/s12974-015-0238-3 |
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