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Evolution of p53 Transactivation Specificity through the Lens of a Yeast-Based Functional Assay

Co-evolution of transcription factors (TFs) with their respective cis-regulatory network enhances functional diversity in the course of evolution. We present a new approach to investigate transactivation capacity of sequence-specific TFs in evolutionary studies. Saccharomyces cerevisiae was used as...

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Detalles Bibliográficos
Autores principales:	Lion, Mattia, Raimondi, Ivan, Donati, Stefano, Jousson, Olivier, Ciribilli, Yari, Inga, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323202/ https://www.ncbi.nlm.nih.gov/pubmed/25668429 http://dx.doi.org/10.1371/journal.pone.0116177

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