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Examination of Candidate Exonic Variants for Association to Alzheimer Disease in the Amish
Alzheimer disease (AD) is the most common cause of dementia. As with many complex diseases, the identified variants do not explain the total expected genetic risk that is based on heritability estimates for AD. Isolated founder populations, such as the Amish, are advantageous for genetic studies as...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323242/ https://www.ncbi.nlm.nih.gov/pubmed/25668194 http://dx.doi.org/10.1371/journal.pone.0118043 |