Cargando…
Examination of Candidate Exonic Variants for Association to Alzheimer Disease in the Amish
Alzheimer disease (AD) is the most common cause of dementia. As with many complex diseases, the identified variants do not explain the total expected genetic risk that is based on heritability estimates for AD. Isolated founder populations, such as the Amish, are advantageous for genetic studies as...
Autores principales: | D’Aoust, Laura N., Cummings, Anna C., Laux, Renee, Fuzzell, Denise, Caywood, Laura, Reinhart-Mercer, Lori, Scott, William K., Pericak-Vance, Margaret A., Haines, Jonathan L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323242/ https://www.ncbi.nlm.nih.gov/pubmed/25668194 http://dx.doi.org/10.1371/journal.pone.0118043 |
Ejemplares similares
-
Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish
por: Waksmunski, Andrea R., et al.
Publicado: (2022) -
Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish
por: Waksmunski, Andrea R., et al.
Publicado: (2019) -
The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish
por: Osterman, Michael D., et al.
Publicado: (2022) -
Founder population-specific weights yield improvements in performance of polygenic risk scores for Alzheimer disease in the Midwestern Amish
por: Osterman, Michael D., et al.
Publicado: (2023) -
The GGLEAM Study: Understanding Glaucoma in the Ohio Amish
por: Waksmunski, Andrea R., et al.
Publicado: (2021)