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A Model of the 2014 Ebola Epidemic in West Africa with Contact Tracing

A differential equations model is developed for the 2014 Ebola epidemics in Sierra Leone and Liberia. The model describes the dynamic interactions of the susceptible and infected populations of these countries. The model incorporates the principle features of contact tracing, namely, the number of c...

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Detalles Bibliográficos
Autores principales: Webb, Glenn, Browne, Cameron, Huo, Xi, Seydi, Ousmane, Seydi, Moussa, Magal, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323422/
https://www.ncbi.nlm.nih.gov/pubmed/25685636
http://dx.doi.org/10.1371/currents.outbreaks.846b2a31ef37018b7d1126a9c8adf22a
Descripción
Sumario:A differential equations model is developed for the 2014 Ebola epidemics in Sierra Leone and Liberia. The model describes the dynamic interactions of the susceptible and infected populations of these countries. The model incorporates the principle features of contact tracing, namely, the number of contacts per identified infectious case, the likelihood that a traced contact is infectious, and the efficiency of the contact tracing process. The model is first fitted to current cumulative reported case data in each country. The data fitted simulations are then projected forward in time, with varying parameter regimes corresponding to contact tracing efficiencies. These projections quantify the importance of the identification, isolation, and contact tracing processes for containment of the epidemics.