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Protective effect of KI in mtDNA in porcine thyroid: comparison with KIO(3) and nDNA

PURPOSE: Iodine, bivalent iron (Fe(2+)), and hydrogen peroxide (H(2)O(2)), all significantly affecting the red-ox balance, are required for thyroid hormone synthesis. Intracellular iodine excess (≥10(−3) M) transiently blocks thyroid hormonogenesis (an adaptive mechanism called Wolff–Chaikoff effect...

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Detalles Bibliográficos
Autores principales: Karbownik-Lewinska, Malgorzata, Stepniak, Jan, Milczarek, Magdalena, Lewinski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323512/
https://www.ncbi.nlm.nih.gov/pubmed/25381633
http://dx.doi.org/10.1007/s00394-014-0797-6