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Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain

Glutamate is an important signaling molecule in a wide variety of tissues. Aberrant glutamatergic signaling disrupts normal tissue homeostasis and induces several disruptive pathological conditions including pain. Breast cancer cells secrete high levels of glutamate and often metastasize to bone. Ex...

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Detalles Bibliográficos
Autores principales: Fazzari, Jennifer, Lin, Hanxin, Murphy, Cecilia, Ungard, Robert, Singh, Gurmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323637/
https://www.ncbi.nlm.nih.gov/pubmed/25670024
http://dx.doi.org/10.1038/srep08380