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Integrin-Linked Kinase links Dynactin-1/Dynactin-2 with cortical Integrin receptors to orient the mitotic spindle relative to the substratum

Cells must divide strictly along a plane to form an epithelial layer parallel to the basal lamina. The axis of cell division is primarily governed by the orientation of the mitotic spindle and spindle misorientation pathways have been implicated in cancer initiation. While β1-Integrin and the Dynein...

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Detalles Bibliográficos
Autores principales:	Morris, Edward James, Assi, Kiran, Salh, Baljinder, Dedhar, Shoukat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323648/ https://www.ncbi.nlm.nih.gov/pubmed/25669897 http://dx.doi.org/10.1038/srep08389

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