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Onychomycosis in patients with chronic leg ulcer and toenail abnormalities()
Nails have a limited number of reactive patterns to disease. Accordingly, toenail changes of different etiologies may mimic onychomycosis. OBJECTIVE: To determine the prevalence of toenail onychomycosis among patients with leg ulcer and toenail abnormalities attending a dermatology clinic. METHODS:...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323716/ https://www.ncbi.nlm.nih.gov/pubmed/25672317 http://dx.doi.org/10.1590/abd1806-4841.20152940 |
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author | Cabete, Joana Galhardas, Célia Apetato, Margarida Lestre, Sara |
author_facet | Cabete, Joana Galhardas, Célia Apetato, Margarida Lestre, Sara |
author_sort | Cabete, Joana |
collection | PubMed |
description | Nails have a limited number of reactive patterns to disease. Accordingly, toenail changes of different etiologies may mimic onychomycosis. OBJECTIVE: To determine the prevalence of toenail onychomycosis among patients with leg ulcer and toenail abnormalities attending a dermatology clinic. METHODS: A cross-sectional study was conducted through the analysis of clinical records and results of mycological examination. RESULTS: A total of 81 patients were included, with a median age of 76.0 years. Most ulcers were of venous etiology, followed by those of mixed and arterial pathogenesis. The mycological evaluation confirmed the diagnosis of onychomycosis in 27.2% of the patients. The etiologic agent was a dermatophyte in 59.1% of isolates in nail samples, while Trichophyton interdigitale was the most frequent fungal species (40.9%). CONCLUSIONS: Most toenail abnormalities in patients with chronic leg ulcer were not onychomycosis. This study highlights the importance of systematic mycological examination in these patients, in order to avoid overtreatment with systemic antifungals, unnecessary costs and side effects. |
format | Online Article Text |
id | pubmed-4323716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-43237162015-02-20 Onychomycosis in patients with chronic leg ulcer and toenail abnormalities() Cabete, Joana Galhardas, Célia Apetato, Margarida Lestre, Sara An Bras Dermatol Communication Nails have a limited number of reactive patterns to disease. Accordingly, toenail changes of different etiologies may mimic onychomycosis. OBJECTIVE: To determine the prevalence of toenail onychomycosis among patients with leg ulcer and toenail abnormalities attending a dermatology clinic. METHODS: A cross-sectional study was conducted through the analysis of clinical records and results of mycological examination. RESULTS: A total of 81 patients were included, with a median age of 76.0 years. Most ulcers were of venous etiology, followed by those of mixed and arterial pathogenesis. The mycological evaluation confirmed the diagnosis of onychomycosis in 27.2% of the patients. The etiologic agent was a dermatophyte in 59.1% of isolates in nail samples, while Trichophyton interdigitale was the most frequent fungal species (40.9%). CONCLUSIONS: Most toenail abnormalities in patients with chronic leg ulcer were not onychomycosis. This study highlights the importance of systematic mycological examination in these patients, in order to avoid overtreatment with systemic antifungals, unnecessary costs and side effects. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4323716/ /pubmed/25672317 http://dx.doi.org/10.1590/abd1806-4841.20152940 Text en ©2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Communication Cabete, Joana Galhardas, Célia Apetato, Margarida Lestre, Sara Onychomycosis in patients with chronic leg ulcer and toenail abnormalities() |
title | Onychomycosis in patients with chronic leg ulcer and toenail
abnormalities()
|
title_full | Onychomycosis in patients with chronic leg ulcer and toenail
abnormalities()
|
title_fullStr | Onychomycosis in patients with chronic leg ulcer and toenail
abnormalities()
|
title_full_unstemmed | Onychomycosis in patients with chronic leg ulcer and toenail
abnormalities()
|
title_short | Onychomycosis in patients with chronic leg ulcer and toenail
abnormalities()
|
title_sort | onychomycosis in patients with chronic leg ulcer and toenail
abnormalities() |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323716/ https://www.ncbi.nlm.nih.gov/pubmed/25672317 http://dx.doi.org/10.1590/abd1806-4841.20152940 |
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