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Effect of Phosphodiesterase Inhibition on Insulin Resistance in Obese Individuals

BACKGROUND: Obesity is associated with cardiometabolic disease, including insulin resistance (IR) and diabetes. Cyclic guanosine monophosphate (cGMP) signaling affects energy balance, IR, and glucose metabolism in experimental models. We sought to examine effects of phosphodiesterase‐5 inhibition wi...

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Detalles Bibliográficos
Autores principales:	Ho, Jennifer E., Arora, Pankaj, Walford, Geoffrey A., Ghorbani, Anahita, Guanaga, Derek P., Dhakal, Bishnu P., Nathan, Daniel I., Buys, Emmanuel S., Florez, Jose C., Newton‐Cheh, Christopher, Lewis, Gregory D., Wang, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323801/ https://www.ncbi.nlm.nih.gov/pubmed/25213566 http://dx.doi.org/10.1161/JAHA.114.001001

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