Anti‐Remodeling and Anti‐Fibrotic Effects of the Neuregulin‐1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure

BACKGROUND: Neuregulin‐1β (NRG‐1β) is a growth factor critical for cardiac development and repair with therapeutic potential for heart failure. We previously showed that the glial growth factor 2 (GGF2) isoform of NRG‐1β improves cardiac function in rodents after myocardial infarction (MI), but its...

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Detalles Bibliográficos
Autores principales: Galindo, Cristi L., Kasasbeh, Ehab, Murphy, Abigail, Ryzhov, Sergey, Lenihan, Sean, Ahmad, Farhaan A., Williams, Philip, Nunnally, Amy, Adcock, Jamie, Song, Yanna, Harrell, Frank E., Tran, Truc‐Linh, Parry, Tom J., Iaci, Jen, Ganguly, Anindita, Feoktistov, Igor, Stephenson, Matthew K., Caggiano, Anthony O., Sawyer, Douglas B., Cleator, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323814/
https://www.ncbi.nlm.nih.gov/pubmed/25341890
http://dx.doi.org/10.1161/JAHA.113.000773

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