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Depletion of B‐Cells With Rituximab Improves Endothelial Function and Reduces Inflammation Among Individuals With Rheumatoid Arthritis
BACKGROUND: Individuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction. B‐cells play an important pathogenic role in the inflammatory process that drives RA disease activity. Rituximab, a chimeric murin...
Autores principales: | Hsue, Priscilla Y., Scherzer, Rebecca, Grunfeld, Carl, Imboden, John, Wu, Yuaner, del Puerto, Gus, Nitta, Elaine, Shigenaga, Judy, Schnell Heringer, Amanda, Ganz, Peter, Graf, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323827/ https://www.ncbi.nlm.nih.gov/pubmed/25336464 http://dx.doi.org/10.1161/JAHA.114.001267 |
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