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Rac1 Signaling Is Critical to Cardiomyocyte Polarity and Embryonic Heart Development
BACKGROUND: Defects in cardiac septation are the most common form of congenital heart disease, but the mechanisms underlying these defects are still poorly understood. The small GTPase Rac1 is implicated in planar cell polarity of epithelial cells in Drosophila; however, its role in mammalian cardio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323834/ https://www.ncbi.nlm.nih.gov/pubmed/25315346 http://dx.doi.org/10.1161/JAHA.114.001271 |