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Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature

Pleomorphic xanthoastrocytoma (PXA) is a rare slow growing tumor which accounts for <1% of all astrocytic neoplasms. PXA usually affects young patients in their second decade of life and carries a favorable prognosis. We present the clinical, radiological and histopathological features of PXA inv...

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Autores principales: Sharma, Mayur, Chaudhery, Shubnum, Sonig, Ashish, Ambekar, Sudheer, Nanda, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323974/
https://www.ncbi.nlm.nih.gov/pubmed/25685227
http://dx.doi.org/10.4103/1793-5482.146635
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author Sharma, Mayur
Chaudhery, Shubnum
Sonig, Ashish
Ambekar, Sudheer
Nanda, Anil
author_facet Sharma, Mayur
Chaudhery, Shubnum
Sonig, Ashish
Ambekar, Sudheer
Nanda, Anil
author_sort Sharma, Mayur
collection PubMed
description Pleomorphic xanthoastrocytoma (PXA) is a rare slow growing tumor which accounts for <1% of all astrocytic neoplasms. PXA usually affects young patients in their second decade of life and carries a favorable prognosis. We present the clinical, radiological and histopathological features of PXA involving the left temporal lobe in an 84-year-old male with right upper motor neuron facial paresis of 2 weeks duration. Histopathology confirmed the diagnosis of PXA. Our case is unique in that our patient is the oldest one reported in the literature with favorable histopathological features. The occurrence of these tumors in elderly patients may indicate an aggressive behavior with unfavorable outcome. Gross total resection achieves higher recurrence free and overall survival rates.
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spelling pubmed-43239742015-02-13 Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature Sharma, Mayur Chaudhery, Shubnum Sonig, Ashish Ambekar, Sudheer Nanda, Anil Asian J Neurosurg Case Report Pleomorphic xanthoastrocytoma (PXA) is a rare slow growing tumor which accounts for <1% of all astrocytic neoplasms. PXA usually affects young patients in their second decade of life and carries a favorable prognosis. We present the clinical, radiological and histopathological features of PXA involving the left temporal lobe in an 84-year-old male with right upper motor neuron facial paresis of 2 weeks duration. Histopathology confirmed the diagnosis of PXA. Our case is unique in that our patient is the oldest one reported in the literature with favorable histopathological features. The occurrence of these tumors in elderly patients may indicate an aggressive behavior with unfavorable outcome. Gross total resection achieves higher recurrence free and overall survival rates. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4323974/ /pubmed/25685227 http://dx.doi.org/10.4103/1793-5482.146635 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sharma, Mayur
Chaudhery, Shubnum
Sonig, Ashish
Ambekar, Sudheer
Nanda, Anil
Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature
title Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature
title_full Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature
title_fullStr Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature
title_full_unstemmed Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature
title_short Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature
title_sort does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323974/
https://www.ncbi.nlm.nih.gov/pubmed/25685227
http://dx.doi.org/10.4103/1793-5482.146635
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