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The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

We previously demonstrated that, in the early stages of tau processing in Alzheimer's disease, the N-terminal part of the molecule undergoes a characteristic cascade of phosphorylation and progressive misfolding of the proteins resulting in a structural conformation detected by Alz-50. In this...

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Detalles Bibliográficos
Autores principales:	Flores-Rodríguez, Paola, Ontiveros-Torres, Miguel A., Cárdenas-Aguayo, María C., Luna-Arias, Juan P., Meraz-Ríos, Marco A., Viramontes-Pintos, Amparo, Harrington, Charles R., Wischik, Claude M., Mena, Raúl, Florán-Garduño, Benjamin, Luna-Muñoz, José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324067/ https://www.ncbi.nlm.nih.gov/pubmed/25717290 http://dx.doi.org/10.3389/fnins.2015.00033

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