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Anti-angiogenic therapeutic strategies in hereditary hemorrhagic telangiectasia

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplastic disorder, characterized by recurrent nosebleeds (epistaxis), multiple telangiectases and arteriovenous malformations (AVMs) in major organs. Mutations in Endoglin (ENG or CD105) and Activin receptor-like kinase...

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Detalles Bibliográficos
Autores principales: Ardelean, Daniela S., Letarte, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324154/
https://www.ncbi.nlm.nih.gov/pubmed/25717337
http://dx.doi.org/10.3389/fgene.2015.00035