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Ribosomal Elongation Factor 4 Promotes Cell Death Associated with Lethal Stress

Ribosomal elongation factor 4 (EF4) is highly conserved among bacteria, mitochondria, and chloroplasts. However, the EF4-encoding gene, lepA, is nonessential and its deficiency shows no growth or fitness defect. In purified systems, EF4 back-translocates stalled, posttranslational ribosomes for effi...

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Detalles Bibliográficos
Autores principales:	Li, Liping, Hong, Yuzhi, Luan, Gan, Mosel, Michael, Malik, Muhammad, Drlica, Karl, Zhao, Xilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324249/ https://www.ncbi.nlm.nih.gov/pubmed/25491353 http://dx.doi.org/10.1128/mBio.01708-14

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