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Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences

By measuring individual mRNA production at the single-cell level, we investigated the lac promoter’s transcriptional transition during cell growth phases. In exponential phase, variation in transition rates generates two mixed phenotypes, low and high numbers of mRNAs, by modulating their burst freq...

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Detalles Bibliográficos
Autores principales:	Sala, Adrien, Shoaib, Muhammad, Anufrieva, Olga, Mutharasu, Gnanavel, Yli-Harja, Olli, Kandhavelu, Meenakshisundaram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324307/ https://www.ncbi.nlm.nih.gov/pubmed/25626902 http://dx.doi.org/10.1128/mBio.02182-14

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