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Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction

Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs...

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Autores principales: Asrar Ul Haq, Muhammad, Goh, Cheng Yee, Levinger, Itamar, Wong, Chiew, Hare, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324467/
https://www.ncbi.nlm.nih.gov/pubmed/25698883
http://dx.doi.org/10.4137/CMC.S21372
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author Asrar Ul Haq, Muhammad
Goh, Cheng Yee
Levinger, Itamar
Wong, Chiew
Hare, David L
author_facet Asrar Ul Haq, Muhammad
Goh, Cheng Yee
Levinger, Itamar
Wong, Chiew
Hare, David L
author_sort Asrar Ul Haq, Muhammad
collection PubMed
description Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs for HF patients over and above the optimal medical therapy. Some of the documented benefits include improved functional capacity, quality of life (QoL), fatigue, and dyspnea. Major trials to assess exercise training in HF have, however, focused on heart failure with reduced ejection fraction (HFREF). At least half of the patients presenting with HF have heart failure with preserved ejection fraction (HFPEF) and experience similar symptoms of exercise intolerance, dyspnea, and early fatigue, and similar mortality risk and rehospitalization rates. The role of exercise training in the management of HFPEF remains less clear. This article provides a brief overview of pathophysiology of reduced exercise tolerance in HFREF and heart failure with preserved ejection fraction (HFPEF), and summarizes the evidence and mechanisms by which exercise training can improve symptoms and HF. Clinical and practical aspects of exercise training prescription are also discussed.
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spelling pubmed-43244672015-02-19 Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction Asrar Ul Haq, Muhammad Goh, Cheng Yee Levinger, Itamar Wong, Chiew Hare, David L Clin Med Insights Cardiol Review Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs for HF patients over and above the optimal medical therapy. Some of the documented benefits include improved functional capacity, quality of life (QoL), fatigue, and dyspnea. Major trials to assess exercise training in HF have, however, focused on heart failure with reduced ejection fraction (HFREF). At least half of the patients presenting with HF have heart failure with preserved ejection fraction (HFPEF) and experience similar symptoms of exercise intolerance, dyspnea, and early fatigue, and similar mortality risk and rehospitalization rates. The role of exercise training in the management of HFPEF remains less clear. This article provides a brief overview of pathophysiology of reduced exercise tolerance in HFREF and heart failure with preserved ejection fraction (HFPEF), and summarizes the evidence and mechanisms by which exercise training can improve symptoms and HF. Clinical and practical aspects of exercise training prescription are also discussed. Libertas Academica 2015-02-09 /pmc/articles/PMC4324467/ /pubmed/25698883 http://dx.doi.org/10.4137/CMC.S21372 Text en © 2015 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license.
spellingShingle Review
Asrar Ul Haq, Muhammad
Goh, Cheng Yee
Levinger, Itamar
Wong, Chiew
Hare, David L
Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_full Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_fullStr Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_full_unstemmed Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_short Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_sort clinical utility of exercise training in heart failure with reduced and preserved ejection fraction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324467/
https://www.ncbi.nlm.nih.gov/pubmed/25698883
http://dx.doi.org/10.4137/CMC.S21372
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