A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis

The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute inhibition of IKK-ε and TBK1 with amlexanox t...

Descripción completa

Detalles Bibliográficos
Autores principales: Reilly, Shannon M., Ahmadian, Maryam, Zamarron, Brian F., Chang, Louise, Uhm, Maeran, Poirier, BreAnne, Peng, Xiaoling, Krause, Danielle M., Korytnaya, Evgenia, Neidert, Adam, Liddle, Christopher, Yu, Ruth T., Lumeng, Carey N., Oral, Elif A., Downes, Michael, Evans, Ronald M., Saltiel, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324568/
https://www.ncbi.nlm.nih.gov/pubmed/25581158
http://dx.doi.org/10.1038/ncomms7047

Ejemplares similares

Ejemplares similares