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Sustained Macrophage Infiltration upon Multiple Intra-Articular Injections: An Improved Rat Model of Rheumatoid Arthritis for PET Guided Therapy Evaluation

To widen the therapeutic window for PET guided evaluation of novel anti-RA agents, modifications were made in a rat model of rheumatoid arthritis (RA). Arthritis was induced in the right knee of Wistar rats with repeated boosting to prolong articular inflammation. The contralateral knee served as co...

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Detalles Bibliográficos
Autores principales:	Chandrupatla, Durga M. S. H., Weijers, Karin, Gent, Yoony Y. J., de Greeuw, Inge, Lammertsma, Adriaan A., Jansen, Gerrit, van der Laken, Conny J., Molthoff, Carla F. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324741/ https://www.ncbi.nlm.nih.gov/pubmed/25695087 http://dx.doi.org/10.1155/2015/509295

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