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Synergistic Interaction between Selective Drugs in Cell Populations Models

The design of selective drugs and combinatorial drug treatments are two of the main focuses in modern pharmacology. In this study we use a mathematical model of chimeric ligand-receptor interaction to show that the combination of selective drugs is synergistic in nature, providing a way to gain opti...

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Detalles Bibliográficos
Autores principales: Doldán-Martelli, Victoria, Míguez, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324767/
https://www.ncbi.nlm.nih.gov/pubmed/25671700
http://dx.doi.org/10.1371/journal.pone.0117558