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Synergistic Interaction between Selective Drugs in Cell Populations Models
The design of selective drugs and combinatorial drug treatments are two of the main focuses in modern pharmacology. In this study we use a mathematical model of chimeric ligand-receptor interaction to show that the combination of selective drugs is synergistic in nature, providing a way to gain opti...
Autores principales: | Doldán-Martelli, Victoria, Míguez, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324767/ https://www.ncbi.nlm.nih.gov/pubmed/25671700 http://dx.doi.org/10.1371/journal.pone.0117558 |
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