Small Molecule Inhibitor of Type Three Secretion Suppresses Acute and Chronic Chlamydia trachomatis Infection in a Novel Urogenital Chlamydia Model

Previously, we reported that a compound from a group of thiohydrazides of oxamic acids, CL-55, possessed antichlamydial activity in vitro that was accompanied by a decreased translocation of the type three secretion effector, IncA, into the host cell. In this study, the antichlamydial activity of CL...

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Detalles Bibliográficos
Autores principales: Koroleva, Ekaterina A., Kobets, Natalia V., Zayakin, Egor S., Luyksaar, Sergei I., Shabalina, Ludmila A., Zigangirova, Naylia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324818/
https://www.ncbi.nlm.nih.gov/pubmed/25695086
http://dx.doi.org/10.1155/2015/484853

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