Effects of 5-Fluorouracil on Morphology, Cell Cycle, Proliferation, Apoptosis, Autophagy and ROS Production in Endothelial Cells and Cardiomyocytes

Antimetabolites are a class of effective anticancer drugs interfering in essential biochemical processes. 5-Fluorouracil (5-FU) and its prodrug Capecitabine are widely used in the treatment of several solid tumors (gastro-intestinal, gynecological, head and neck, breast carcinomas). Therapy with flu...

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Detalles Bibliográficos
Autores principales: Focaccetti, Chiara, Bruno, Antonino, Magnani, Elena, Bartolini, Desirée, Principi, Elisa, Dallaglio, Katiuscia, Bucci, Eraldo O., Finzi, Giovanna, Sessa, Fausto, Noonan, Douglas M., Albini, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324934/
https://www.ncbi.nlm.nih.gov/pubmed/25671635
http://dx.doi.org/10.1371/journal.pone.0115686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324934/
https://www.ncbi.nlm.nih.gov/pubmed/25671635
http://dx.doi.org/10.1371/journal.pone.0115686

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