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Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures
Novel spheroid-type tumor cell cultures directly isolated from patients’ tumors preserve tumor characteristics better than traditionally grown cell lines. However, such cultures are not generally used for high-throughput toxicity drug screens. In addition, the assays that are commonly used to assess...
Autores principales: | Trumpi, Kari, Egan, David A., Vellinga, Thomas T., Borel Rinkes, Inne H.M., Kranenburg, Onno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325131/ https://www.ncbi.nlm.nih.gov/pubmed/25685667 http://dx.doi.org/10.1016/j.fob.2015.01.003 |
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