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Isocitrate dehydrogenase 1 mutations (IDH1) and p16/CDKN2A copy number change in conventional chondrosarcomas

To determine whether IDH1 mutations are present in primary and relapsed (local and distal) conventional central chondrosarcomas; and secondly, to assess if loss of p16/CDKN2A is associated with tumour grade progression, 102 tumour samples from 37 patients, including material from presenting and rela...

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Detalles Bibliográficos
Autores principales:	Amary, M. Fernanda, Ye, Hongtao, Forbes, Georgina, Damato, Stephen, Maggiani, Francesca, Pollock, Robin, Tirabosco, Roberto, Flanagan, Adrienne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325180/ https://www.ncbi.nlm.nih.gov/pubmed/25432631 http://dx.doi.org/10.1007/s00428-014-1685-4

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