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Disequilibrium of BMP2 Levels in the Breast Stem Cell Niche Launches Epithelial Transformation by Overamplifying BMPR1B Cell Response

Understanding the mechanisms of cancer initiation will help to prevent and manage the disease. At present, the role of the breast microenvironment in transformation remains unknown. As BMP2 and BMP4 are important regulators of stem cells and their niches in many tissues, we investigated their functi...

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Detalles Bibliográficos
Autores principales:	Chapellier, Marion, Bachelard-Cascales, Elodie, Schmidt, Xenia, Clément, Flora, Treilleux, Isabelle, Delay, Emmanuel, Jammot, Alexandre, Ménétrier-Caux, Christine, Pochon, Gaëtan, Besançon, Roger, Voeltzel, Thibault, Caron de Fromentel, Claude, Caux, Christophe, Blay, Jean-Yves, Iggo, Richard, Maguer-Satta, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325271/ https://www.ncbi.nlm.nih.gov/pubmed/25601208 http://dx.doi.org/10.1016/j.stemcr.2014.12.007

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