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Energetics and Structural Characterization of the large-scale Functional Motion of Adenylate Kinase

Adenylate Kinase (AK) is a signal transducing protein that regulates cellular energy homeostasis balancing between different conformations. An alteration of its activity can lead to severe pathologies such as heart failure, cancer and neurodegenerative diseases. A comprehensive elucidation of the la...

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Detalles Bibliográficos
Autores principales:	Formoso, Elena, Limongelli, Vittorio, Parrinello, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325324/ https://www.ncbi.nlm.nih.gov/pubmed/25672826 http://dx.doi.org/10.1038/srep08425

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