Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Motivation: Inferring how humans respond to external cues such as drugs, chemicals, viruses or hormones is an essential question in biomedicine. Very often, however, this question cannot be addressed because it is not possible to perform experiments in humans. A reasonable alternative consists of ge...

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Detalles Bibliográficos
Autores principales: Rhrissorrakrai, Kahn, Belcastro, Vincenzo, Bilal, Erhan, Norel, Raquel, Poussin, Carine, Mathis, Carole, Dulize, Rémi H. J., Ivanov, Nikolai V., Alexopoulos, Leonidas, Jeremy Rice, J., Peitsch, Manuel C., Stolovitzky, Gustavo, Meyer, Pablo, Hoeng, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Improver Challenge Special Issue; Species Translation Challenge
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325540/
https://www.ncbi.nlm.nih.gov/pubmed/25236459
http://dx.doi.org/10.1093/bioinformatics/btu611

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