A crowd-sourcing approach for the construction of species-specific cell signaling networks

Motivation: Animal models are important tools in drug discovery and for understanding human biology in general. However, many drugs that initially show promising results in rodents fail in later stages of clinical trials. Understanding the commonalities and differences between human and rat cell sig...

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Detalles Bibliográficos
Autores principales: Bilal, Erhan, Sakellaropoulos, Theodore, Participants, Challenge, Melas, Ioannis N., Messinis, Dimitris E., Belcastro, Vincenzo, Rhrissorrakrai, Kahn, Meyer, Pablo, Norel, Raquel, Iskandar, Anita, Blaese, Elise, Rice, John J., Peitsch, Manuel C., Hoeng, Julia, Stolovitzky, Gustavo, Alexopoulos, Leonidas G., Poussin, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Improver Challenge Special Issue; Species Translation Challenge
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325542/
https://www.ncbi.nlm.nih.gov/pubmed/25294919
http://dx.doi.org/10.1093/bioinformatics/btu659

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