Incidental Merkel cell carcinoma in a cutaneous horn: a case report

Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a co...

Descripción completa

Detalles Bibliográficos
Autores principales: Schick, Brian A., Tobe, Joshua S., Joseph, Mariamma G., Rouse, Tyler B., Gabril, Manal Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Derm101.com 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325691/
https://www.ncbi.nlm.nih.gov/pubmed/25692082
http://dx.doi.org/10.5826/dpc.0501a08
_version_ 1782356846829371392
author Schick, Brian A.
Tobe, Joshua S.
Joseph, Mariamma G.
Rouse, Tyler B.
Gabril, Manal Y.
author_facet Schick, Brian A.
Tobe, Joshua S.
Joseph, Mariamma G.
Rouse, Tyler B.
Gabril, Manal Y.
author_sort Schick, Brian A.
collection PubMed
description Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.
format Online
Article
Text
id pubmed-4325691
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Derm101.com
record_format MEDLINE/PubMed
spelling pubmed-43256912015-02-17 Incidental Merkel cell carcinoma in a cutaneous horn: a case report Schick, Brian A. Tobe, Joshua S. Joseph, Mariamma G. Rouse, Tyler B. Gabril, Manal Y. Dermatol Pract Concept Original Research Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn. Derm101.com 2015-01-30 /pmc/articles/PMC4325691/ /pubmed/25692082 http://dx.doi.org/10.5826/dpc.0501a08 Text en Copyright: ©2015 Schick et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Research
Schick, Brian A.
Tobe, Joshua S.
Joseph, Mariamma G.
Rouse, Tyler B.
Gabril, Manal Y.
Incidental Merkel cell carcinoma in a cutaneous horn: a case report
title Incidental Merkel cell carcinoma in a cutaneous horn: a case report
title_full Incidental Merkel cell carcinoma in a cutaneous horn: a case report
title_fullStr Incidental Merkel cell carcinoma in a cutaneous horn: a case report
title_full_unstemmed Incidental Merkel cell carcinoma in a cutaneous horn: a case report
title_short Incidental Merkel cell carcinoma in a cutaneous horn: a case report
title_sort incidental merkel cell carcinoma in a cutaneous horn: a case report
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325691/
https://www.ncbi.nlm.nih.gov/pubmed/25692082
http://dx.doi.org/10.5826/dpc.0501a08
work_keys_str_mv AT schickbriana incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT tobejoshuas incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT josephmariammag incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT rousetylerb incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT gabrilmanaly incidentalmerkelcellcarcinomainacutaneoushornacasereport

Ejemplares similares