Cargando…

Asef controls vascular endothelial permeability and barrier recovery in the lung

Increased levels of hepatocyte growth factor (HGF) in injured lungs may reflect a compensatory response to diminish acute lung injury (ALI). HGF-induced activation of Rac1 GTPase stimulates endothelial barrier protective mechanisms. This study tested the involvement of Rac-specific guanine nucleotid...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Xinyong, Tian, Yufeng, Gawlak, Grzegorz, Meng, Fanyong, Kawasaki, Yoshihiro, Akiyama, Tetsu, Birukova, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325835/
https://www.ncbi.nlm.nih.gov/pubmed/25518936
http://dx.doi.org/10.1091/mbc.E14-02-0725