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Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology

Seipin is necessary for both adipogenesis and lipid droplet (LD) organization in nonadipose tissues; however, its molecular function is incompletely understood. Phenotypes in the seipin-null mutant of Saccharomyces cerevisiae include aberrant droplet morphology (endoplasmic reticulum–droplet cluster...

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Detalles Bibliográficos
Autores principales: Cartwright, Bethany R., Binns, Derk D., Hilton, Christopher L., Han, Sungwon, Gao, Qiang, Goodman, Joel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325842/
https://www.ncbi.nlm.nih.gov/pubmed/25540432
http://dx.doi.org/10.1091/mbc.E14-08-1303