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Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology
Seipin is necessary for both adipogenesis and lipid droplet (LD) organization in nonadipose tissues; however, its molecular function is incompletely understood. Phenotypes in the seipin-null mutant of Saccharomyces cerevisiae include aberrant droplet morphology (endoplasmic reticulum–droplet cluster...
Autores principales: | Cartwright, Bethany R., Binns, Derk D., Hilton, Christopher L., Han, Sungwon, Gao, Qiang, Goodman, Joel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325842/ https://www.ncbi.nlm.nih.gov/pubmed/25540432 http://dx.doi.org/10.1091/mbc.E14-08-1303 |
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