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Toxicogenomics profiling of bone marrow from rats treated with topotecan in combination with oxaliplatin: a mechanistic strategy to inform combination toxicity

Combinations of anticancer agents may have synergistic anti-tumor effects, but enhanced hematological toxicity often limit their clinical use. We examined whether “microarray profiles” could be used to compare early molecular responses following a single dose of agents administered individually with...

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Detalles Bibliográficos
Autores principales: Davis, Myrtle, Li, Jianying, Knight, Elaine, Eldridge, Sandy R., Daniels, Kellye K., Bushel, Pierre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325931/
https://www.ncbi.nlm.nih.gov/pubmed/25729387
http://dx.doi.org/10.3389/fgene.2015.00014

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