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ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions

Interleukin-1β is a potent proinflammatory cytokine, of which processing and secretion are tightly regulated. After exposure to various stimuli, mononuclear phagocytes synthesize the inactive precursor (pro-IL-1β), which is then cleaved intracellularly by caspase-1 and secreted. A widely used method...

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Detalles Bibliográficos
Autores principales:	Stoffels, Monique, Zaal, Ruben, Kok, Nina, van der Meer, Jos W. M., Dinarello, Charles A., Simon, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325933/ https://www.ncbi.nlm.nih.gov/pubmed/25729382 http://dx.doi.org/10.3389/fimmu.2015.00054

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