TNF-α and IGF1 modify the microRNA signature in skeletal muscle cell differentiation

BACKGROUND: Elevated levels of the inflammatory cytokine TNF-α are common in chronic diseases or inherited or degenerative muscle disorders and can lead to muscle wasting. By contrast, IGF1 has a growth promoting effect on skeletal muscle. The molecular mechanisms mediating the effect of TNF-α and I...

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Detalles Bibliográficos
Autores principales: Meyer, Swanhild U, Thirion, Christian, Polesskaya, Anna, Bauersachs, Stefan, Kaiser, Sebastian, Krause, Sabine, Pfaffl, Michael W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325962/
https://www.ncbi.nlm.nih.gov/pubmed/25630602
http://dx.doi.org/10.1186/s12964-015-0083-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325962/
https://www.ncbi.nlm.nih.gov/pubmed/25630602
http://dx.doi.org/10.1186/s12964-015-0083-0

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