Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation

Nelfinavir (NFV) is an HIV-1 aspartyl protease inhibitor that has numerous effects on human cells, which impart attractive antitumor properties. NFV has also been shown to have in vitro inhibitory activity against human herpesviruses (HHVs). Given the apparent absence of an aspartyl protease encoded...

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Detalles Bibliográficos
Autores principales: Gantt, Soren, Gachelet, Eliora, Carlsson, Jacquelyn, Barcy, Serge, Casper, Corey, Lagunoff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325974/
https://www.ncbi.nlm.nih.gov/pubmed/25709648
http://dx.doi.org/10.1155/2015/687162

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