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Molecular Signatures in the Prevention of Radiation Damage by the Synergistic Effect of N-Acetyl Cysteine and Qingre Liyan Decoction, a Traditional Chinese Medicine, Using a 3-Dimensional Cell Culture Model of Oral Mucositis

Qingre Liyan decoction (QYD), a Traditional Chinese medicine, and N-acetyl cysteine (NAC) have been used to prevent radiation induced mucositis. This work evaluates the protective mechanisms of QYD, NAC, and their combination (NAC-QYD) at the cellular and transcriptional level. A validated organotyp...

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Detalles Bibliográficos
Autores principales: Lambros, Maria P., Kondapalli, Lavanya, Parsa, Cyrus, Mulamalla, Hari Chandana, Orlando, Robert, Pon, Doreen, Huang, Ying, Chow, Moses S. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326035/
https://www.ncbi.nlm.nih.gov/pubmed/25705238
http://dx.doi.org/10.1155/2015/425760