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Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells
Doxorubicin is a chemotherapeutic agent indicated for the treatment of a variety of cancer types, including leukaemia, lymphomas, and many solid tumours. The use of doxorubicin is, however, associated with severe cardiotoxicity, often resulting in early discontinuation of the treatment. Importantly,...
Autores principales: | Holmgren, Gustav, Synnergren, Jane, Bogestål, Yalda, Améen, Caroline, Åkesson, Karolina, Holmgren, Sandra, Lindahl, Anders, Sartipy, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326176/ https://www.ncbi.nlm.nih.gov/pubmed/25529476 http://dx.doi.org/10.1016/j.tox.2014.12.018 |
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