RAD18 Activates the G2/M Checkpoint through DNA Damage Signaling to Maintain Genome Integrity after Ionizing Radiation Exposure

The ubiquitin ligase RAD18 is involved in post replication repair pathways via its recruitment to stalled replication forks, and its role in the ubiquitylation of proliferating cell nuclear antigen (PCNA). Recently, it has been reported that RAD18 is also recruited to DNA double strand break (DSB) s...

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Detalles Bibliográficos
Autores principales: Sasatani, Megumi, Xu, Yanbin, Kawai, Hidehiko, Cao, Lili, Tateishi, Satoshi, Shimura, Tsutomu, Li, Jianxiang, Iizuka, Daisuke, Noda, Asao, Hamasaki, Kanya, Kusunoki, Yoichiro, Kamiya, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326275/
https://www.ncbi.nlm.nih.gov/pubmed/25675240
http://dx.doi.org/10.1371/journal.pone.0117845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326275/
https://www.ncbi.nlm.nih.gov/pubmed/25675240
http://dx.doi.org/10.1371/journal.pone.0117845

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