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Male-specific hepatitis B virus large surface protein variant W4P potentiates tumorigenicity and induces gender disparity

BACKGROUND: The underlying mechanisms of carcinogenesis and gender disparity in hepatitis B virus (HBV)-induced hepatocellular carcinoma (HCC) remain unclear. Recently, we reported a novel HCC-related W4P/R mutation in the large surface protein (LHB) of HBV genotype C, which was found exclusively in...

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Detalles Bibliográficos
Autores principales:	Lee, Seoung-Ae, Kim, Hong, Won, You-Sub, Seok, Seung-Hyeok, Na, YiRang, Shin, Han-Bo, Inn, Kyung-Soo, Kim, Bum-Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326317/ https://www.ncbi.nlm.nih.gov/pubmed/25645622 http://dx.doi.org/10.1186/s12943-015-0303-7

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