Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies

Chronic spontaneous urticaria is an itching skin disease characterised by wheals, angioedema, or both present for more than six weeks. Omalizumab is a humanized anti-IgE monoclonal antibody recently approved for treatment of chronic urticaria. Several randomised controlled trials have investigated t...

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Detalles Bibliográficos
Autores principales: Ghazanfar, Misbah Nasheela, Thomsen, Simon Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326346/
https://www.ncbi.nlm.nih.gov/pubmed/25705229
http://dx.doi.org/10.1155/2015/368053
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author Ghazanfar, Misbah Nasheela
Thomsen, Simon Francis
author_facet Ghazanfar, Misbah Nasheela
Thomsen, Simon Francis
author_sort Ghazanfar, Misbah Nasheela
collection PubMed
description Chronic spontaneous urticaria is an itching skin disease characterised by wheals, angioedema, or both present for more than six weeks. Omalizumab is a humanized anti-IgE monoclonal antibody recently approved for treatment of chronic urticaria. Several randomised controlled trials have investigated the safety, tolerability, and efficacy of omalizumab for chronic urticaria. The safety of omalizumab in pregnancy is not known. We describe a female patient with chronic spontaneous urticaria who was treated with omalizumab continuously through two consecutive pregnancies with convincing results and no apparent toxicity.
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spelling pubmed-43263462015-02-22 Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies Ghazanfar, Misbah Nasheela Thomsen, Simon Francis Case Rep Med Case Report Chronic spontaneous urticaria is an itching skin disease characterised by wheals, angioedema, or both present for more than six weeks. Omalizumab is a humanized anti-IgE monoclonal antibody recently approved for treatment of chronic urticaria. Several randomised controlled trials have investigated the safety, tolerability, and efficacy of omalizumab for chronic urticaria. The safety of omalizumab in pregnancy is not known. We describe a female patient with chronic spontaneous urticaria who was treated with omalizumab continuously through two consecutive pregnancies with convincing results and no apparent toxicity. Hindawi Publishing Corporation 2015 2015-01-29 /pmc/articles/PMC4326346/ /pubmed/25705229 http://dx.doi.org/10.1155/2015/368053 Text en Copyright © 2015 M. N. Ghazanfar and S. F. Thomsen. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ghazanfar, Misbah Nasheela
Thomsen, Simon Francis
Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies
title Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies
title_full Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies
title_fullStr Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies
title_full_unstemmed Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies
title_short Successful and Safe Treatment of Chronic Spontaneous Urticaria with Omalizumab in a Woman during Two Consecutive Pregnancies
title_sort successful and safe treatment of chronic spontaneous urticaria with omalizumab in a woman during two consecutive pregnancies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326346/
https://www.ncbi.nlm.nih.gov/pubmed/25705229
http://dx.doi.org/10.1155/2015/368053
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AT thomsensimonfrancis successfulandsafetreatmentofchronicspontaneousurticariawithomalizumabinawomanduringtwoconsecutivepregnancies

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