Diabetes Mellitus Accelerates Aβ Pathology in Brain Accompanied by Enhanced GAβ Generation in Nonhuman Primates

Growing evidence suggests that diabetes mellitus (DM) is one of the strongest risk factors for developing Alzheimer’s disease (AD). However, it remains unclear why DM accelerates AD pathology. In cynomolgus monkeys older than 25 years, senile plaques (SPs) are spontaneously and consistently observed...

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Detalles Bibliográficos
Autores principales: Okabayashi, Sachi, Shimozawa, Nobuhiro, Yasutomi, Yasuhiro, Yanagisawa, Katsuhiko, Kimura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326359/
https://www.ncbi.nlm.nih.gov/pubmed/25675436
http://dx.doi.org/10.1371/journal.pone.0117362

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