Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence

INTRODUCTION: Elafin is an endogenous serine protease inhibitor. The majority of breast cancer cell lines lack elafin expression compared to human mammary epithelial cells. In this study, we hypothesized that elafin is downregulated during breast and ovarian tumorigenesis. METHODS: We examined elafi...

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Detalles Bibliográficos
Autores principales: Caruso, Joseph A, Karakas, Cansu, Zhang, Jing, Yi, Min, Albarracin, Constance, Sahin, Aysegul, Bondy, Melissa, Liu, Jinsong, Hunt, Kelly K, Keyomarsi, Khandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326485/
https://www.ncbi.nlm.nih.gov/pubmed/25551582
http://dx.doi.org/10.1186/s13058-014-0497-4

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